They began occurring in standard Notes after installing FP6IF6 to 8.5.3.
The biggest thing I've observed is that the workspace quits responding to mouse clicks. Other tabs seem fine, but specifically the workspace collapses.
The issues below had existed prior to this fixpack as well. But something seems delayed in the startup, and it's aggravating them
The user policy settings seem to be delayed in being retrieved from the home server, and while those policy settings are being retrieved, Notes seems to risk crashing or freezing completely when you attempt certain menu items from the desktop. It's hard to be specific, but trying to get an application's database properties; launch an agent without opening the database (to another window); copy a database.
It seems much more often, the bookmark.nsf is corrupted. I have been shutting down Notes and watching it roll off task manager's process list since ND7, before I log out. But now that's no assurance that bookmark.nsf is uncorrupted. In most cases, the Notes splash screen remains in "Loading... Please wait" and the progress bar cycles three or more times without loading Notes. If I kill Notes processes, then run nfixup -V -Q bookmark.nsf, the issue disappears.